A variety of amino acids, vitamins and polysaccharides and other efficient fermentation technology

Technical information

1. Introduction and background of achievements;

Amino acids, organic acids and polysaccharides are widely used in feed, food additives, medicine and other fields, with large market demand and high output value.

Such as used in the field of feed L-lysine, L-threonine, L-tryptophan and so on.

In addition, some small varieties of amino acids because of their special physiological functions, can be used in beverages, health products and special foods and other fields, the market prospect is good.

This project uses synthetic biotechnology to construct engineering bacteria and efficiently fermentation a variety of amino acids, including L-tryptophan, 5-hydroxytryptophan, L-homoserine, L-arginine, L-ornithine, L-threonine, L-homophenylalanine and so on.

2. technical advantages, performance indicators, corresponding products, etc.

This project uses advanced synthetic biotechnology to construct a variety of highly efficient strains for amino acid production.

The 5-hydroxytryptophan fermentation acid production level reached 28-30 g/L;
The acid production level of L-homoserine fermentation reached about 130 g/L.
L-arginine fermentation acid production level 100 g/L;
L-isoleucine fermentation acid production level 45-50 g/L;
L-tryptophan fermentation acid production level reached about 50 g/L;
L-valine fermentation acid production level 90-110 g/L;
L-ornithine fermentation acid production level 100 g/L;
L-threonine fermentation acid production level 130-140 g/L;
L-lysine fermentation acid production level 210-230 g/L;
L-glutamic acid fermentation level 200-220 g/L.
Citric acid fermentation level 160-170 g/L.
Vitamin K2 fermentation level reached 1 g/L.
α-cyclodextrin concentrations reached 210-230 g/L.
Glycerol glucoside concentration reached 220 g/L.
Glucosamine fermentation level 130 g/L.
Hyaluronic acid fermentation level 15 g/L.

A variety of other gammacyclodextrins, rhamnose-lipids, p-hydroxyacetophenone, and more are under development.

3. Project maturity;

The product has completed the pilot test, and a number of products have been applied to enterprise production.

4. Application and market

Amino acids can be used in feed, food additives and medicine and other fields, the market demand is large, high output value.

Taking L-tryptophan as an example, its current domestic production is 20,000 tons/year, the demand is more than 30,000 tons, and the gap is 10,000 tons, relying on imports to meet the demand.

With the implementation of the three-year action plan for soybean meal replacement by the Ministry of Agriculture, the demand for essential amino acids has increased significantly, and the domestic market for L-tryptophan will usher in great opportunities for development in the future.